Detalhe da pesquisa
1.
AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor.
Mol Syst Biol
; 20(4): 428-457, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38467836
2.
The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape.
PLoS Pathog
; 17(9): e1009919, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34543356
3.
Kinetic and thermodynamic characterisation of HIV-protease inhibitors against E35D↑G↑S mutant in the South African HIV-1 subtype C protease.
J Enzyme Inhib Med Chem
; 34(1): 1451-1456, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31409143
4.
An insight to the molecular interactions of the FDA approved HIV PR drugs against L38L↑N↑L PR mutant.
J Comput Aided Mol Des
; 32(3): 459-471, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29397520
5.
A systematic approach to identify host targets and rapidly deliver broad-spectrum antivirals.
Mol Ther
; 30(5): 1797-1800, 2022 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35231394
6.
I36T↑T mutation in South African subtype C (C-SA) HIV-1 protease significantly alters protease-drug interactions.
Biol Chem
; 398(10): 1109-1117, 2017 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-28525359
7.
Purification and characterization of naturally occurring HIV-1 (South African subtype C) protease mutants from inclusion bodies.
Protein Expr Purif
; 122: 90-6, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26917227
8.
Identification of small molecule antivirals against HTLV-1 by targeting the hDLG1-Tax-1 protein-protein interaction.
Antiviral Res
; 217: 105675, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37481039
9.
AI-guided pipeline for protein-protein interaction drug discovery identifies a SARS-CoV-2 inhibitor.
bioRxiv
; 2023 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37398436
10.
A proteome-scale map of the SARS-CoV-2-human contactome.
Nat Biotechnol
; 41(1): 140-149, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36217029
11.
Mechanistic insight on the inhibition of D, D-carboxypeptidase from Mycobacterium tuberculosis by ß-lactam antibiotics: an ONIOM acylation study.
J Biomol Struct Dyn
; 40(17): 7645-7655, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33719919
12.
Optimized Procedure for Recovering HIV-1 Protease (C-SA) from Inclusion Bodies.
Protein J
; 38(1): 30-36, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30666487
13.
Identification of potent L,D-transpeptidase 5 inhibitors for Mycobacterium tuberculosis as potential anti-TB leads: virtual screening and molecular dynamics simulations.
J Mol Model
; 25(11): 328, 2019 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31656981
14.
Exploring the flap dynamics of the South African HIV subtype C protease in presence of FDA-approved inhibitors: MD study.
Chem Biol Drug Des
; 92(5): 1899-1913, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30003668